In the case of depression, a number of centres responsible for regulating mood have been identified. Poor regulation of these centres can lead to depressive symptoms. Depression is a disorder that differs from usual mood swings as well as brief emotional responses to problematic situations that arise in everyday life. It affects to health seriously, causing great suffering and altering the activities carried out by the individual who suffers.
In depression disorder, it is established that the prefrontal cortex, amygdala and hippocampus, are responsible for mood, so poor regulation or instability in any of these elements can trigger depressive symptoms.